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The underlying mechanism is as follows: in the presence of the terminal electron acceptor -oxygen- the electron transport chain maintains oxidation of NADH to NAD + by complex I, and this NAD + is supporting dehydrogenases, including the pyruvate dehydrogenase complex

Most patients on GLP-1 therapy lose 1-2 pounds per week, so monitoring TSH every 6-8 weeks during active weight loss helps catch any need for dose changes early

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An excess of this medication can lead to severe hypoglycemia, nausea, vomiting, and abdominal pain among other symptoms, and these symptoms can be dangerous if not treated promptly and properly