Both act on the same GHRH receptor, so the difference is stability and duration rather than mechanism
The tissues were rinsed with PBS and incubated with Alexa Fluor488 chicken anti-rabbit (1:1000, Life Technologies) for one hour at 37 C and then rinsed with PBS and incubated with Alexa Fluor488 goat anti-chicken antibody (1:1000, Life Technologies) and Alexa Fluor568 goat anti-mouse antibody (1:1000, Life Technologies) for another hour at 37 C
Rajan PK, Udoh UA, Sanabria JD, Banerjee M, Smith G, Schade MS, et al
Brain and spinal cord lesions (scored 05, or 13, Min/Med/Max) in rats that received cuprizone diet, and then cuprizone intragastrical applications, and thereby, cuprizone toxicity manifestations