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"Is glucagon receptor activation the thermogenic solution for treating obesity?" Frontiers in Endocrinology

Mar 1 2022;5(3):e222983

The results demonstrated that there is a strong direct correlation between baseline A1c level and the magnitude of the decrease in fasting glucose and A1c induced by these drugs (i.e., significantly greater reductions in both fasting plasma glucose and A1c were observed in groups with higher baseline A1c levels)

Populations to avoid: Pregnant and breastfeeding individuals, individuals with active neuroendocrine conditions, and those on ACTH-axis medications should not use DSIP without specialist guidance