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[DOI] [PubMed] [Google Scholar] 124.Li C., Deng X., Xie X., Liu Y., Friedmann Angeli J.P., Lai L
References for this information: Biochemistry and Cell Biology , 2019, volume 92, issue 3, pages 270-289 Biochemical Pharmacology , 2003, Volume 66, issue 8, pages 1499-1503 International Journal of Biomedical Science , 2008, volume 4, issue 2, pages 89-96 Pharmacology Review, 2010, volume 4, issue 8, pages 118-126 Antioxidants and Redox Signaling , 2013, volume 19, issue 8, pages 813-822 Nutrients , 2019, volume 11, issue 9 Biomolecules , 2015, volume 5, issue 2, pages 545-589 Aging: Oxidative Stress and Dietary Antioxidants , 2014, pages 15-22 Asian Pacific Journal of Cancer Prevention, 2014, volume 15, issue 2, pages 561-568 Clinical, Cosmetic and Investigational Dermatology , 2017, volume 10, pages 147-153 British Society for Immunology , 2020, volume 160, issue 2, pages 116-125 Harvard T.H
In general: Take your thumb and index (pointer) finger and pinch the skin
The resulting strategy families correspond to major design objectives: improving pharmacokinetics and biodistribution [33, 37, 53, 66, 67], modulating vascular access and perfusion [11, 12, 15, 68, 69], normalizing or reprogramming stromal barriers [13, 17, 30, 32, 34, 70], enabling endogenous TME-responsive release or activation [46,47,48], reshaping antitumor immunity [29, 35, 71], and integrating imaging with therapeutic intervention [72,73,74]
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