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Theoretical concerns include angiogenesis-related risk in patients with current or prior cancer, and effects on nitric oxide signaling that could matter for blood pressure

Studies have examined its effects on tendon-to-bone healing, ligament repair, and collagen organisation in pre-clinical injury models making it a central compound for laboratories studying connective tissue regeneration

GLP-1 treatments such as tirzepatide are prescription medications with substantial clinical evidence for weight loss in eligible patients