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Experimental SIV-infections of macaques demonstrate that the virus is seeded into the lungs shortly after intravenous infection ( Upon reaching the lung, HIV is seeded into multiple cell types: CD4 T-cells, DN T-cells, and AMs

Consistently, another study also confirmed these previous experiments by showing a main effect of 250 ng/mL IGF-1 to increase collagen production in 3D and different FBS enriched media, where the constructs were divided into four treatment groups: (1)0.5% FBS, (2) 0.5% FBS+250 ng/mL IGF-1, (3) 10% FBS, (4) 10% FBS+250 ng/mL IGF-1

doi:10.3109/14992027.2016.1143980

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