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It remains uncertain whether GLP-1 receptor activation itself has any direct effect on hair follicle biology, though current evidence does not support this mechanism

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Carnitine has a protective effect on glaucoma-induced retinal ganglion cells injury by reducing the expression of typical markers of cell stress, such as glial fibrillary acidic protein (GFAP), inducible nitric oxide synthase (iNOS), ubiquitin and caspase-3, and reducing the level of the lipid peroxidation product malondialdehyde (MDA) [318]

In a direct obesity trial, tirzepatide produced greater average weight loss, but both commonly caused gastrointestinal side effects