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Molecular mechanisms of increased mucus secretion Secretion of mucins in the airway is continuous, with induced increases in mucin production intracellularly correlating to more concentrated mucin secretion, but secretagogues, such as ATP or histamine, are responsible for the rapid, complete release of granule contents accumulated within mucin-producing cells into the airway lumen (Jaramillo et al., 2018)

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Sci Immunol