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Corresponding author Mohamad Nassereddine, MD, Division of Orthopedic Surgery, American University of Beirut Medical Center, Beirut, Lebanon Email: [email protected]

Am J Physiol Gastrointest Liver Physiol 290:G1339G1346 Guicciardi ME, Bronk SF, Werneburg NW, Yin XM, Gores GJ (2005) Bid is upstream of lysosome-mediated caspase 2 activation in tumor necrosis factor alpha-induced hepatocyte apoptosis