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PubMed, Kamstrup, Pia R., et al

In another meta-analysis including 25 randomized controlled trials involving exenatide, liraglutide, or exenatide LAR, the weighted mean change in body weight in treated individuals compared to controls was -2.9 kg (95% confidence interval, -3.6 to -2.2) [32]

J Am Soc Nephrol 11:14191425 D'Ercole AJ, Stiles AD, Underwood LE (1984) Tissue concentrations of somatomedin C: further evidence for multiple sites of synthesis and paracrine or autocrine mechanisms of action

Quick Answer: Tirzepatide is not contraindicated in Graves disease, but requires individualized assessment with careful thyroid monitoring and is generally deferred until patients achieve euthyroid status