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Regarding shortages of Ozempic, Novo Nordisk said in part, "We ask that healthcare professionals prescribe our medicines consistent with their FDA-approved indications." The company also added that they have been "steadily increasing capacity to produce more Wegovy than ever before." Novo Nordisk noted that Wegovy and Ozempic "are not interchangeable and should not be used outside of their approved indications."

This thermodynamic constraint along with the experimental observations is used to estimate reducing potentials for eumelanin (Fig

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