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The dynamic range of the probe in the cytosol calculated from the respective min and max ratios was about 3-fold (Figure 8C), which is similar to the predictions from the spectral analysis of recombinant roGFP2-iL (Figure 2)

Thus, oxidative stress is greatly involved in the onset and exacerbation of colitis, and it is likely that an appropriate antioxidant could serve as an effective therapeutic agent for UC