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Larger, longer-term studies are needed to establish durability and optimal dosing
In Small JE, Noujaim DL, Ginat DT, Kelly HR (eds.)
12, 16, 18 A high degree of synergistic enhancement of L-PAM cytotoxicity in the presence of BSO was observed in multidrug-resistant neuroblastoma cell lines, including those that were established at relapse after myeloablative therapy with L-PAM and lines highly resistant to L-PAM due to loss of p53 function, especially at concentrations of L-PAM that were myeloablative
The cfu counts of aspirin-treated cells were then presented as fold changes in viability by normalizing them to the cfu counts of untreated cells
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