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GHK-Cu alone is "better" when the research question requires single-mechanism focus

Contrave: Contrave combines two medications, naltrexone and bupropion, which work together to affect the areas of the brain that control eating behavior and appetite

Additionally, a decrease in the level of SST messenger RNA (mRNA) has been reported in several brain regions, including dorsolateral PFC (90, 91), ACC (92) and amygdala (93) in depression (47)