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15,16 Jennings et al 15 demonstrated a significant decrease in weight (6.5 kg), HS Physicians Global Assessment (HS-PGA) (from 4 to 1), DLQI (from 24 to 14), and analgesic use (from daily to not daily) but no decrease in CRP (from 3 mg/dL) after eight weeks of treatment

Melanin provides a barrier for the nuclei of keratinocytes against ultraviolet radiation and also plays a role in the immune system.[5] Langerhans cells, or dendritic cells, are another cell type in the epidermis and have a primary function of antigen presentation

Pharmacol Rev (2008) 60:470512

Copper Peptide can also promote skin repair and regeneration, reduce inflammation, and make skin healthier and younger