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Monitoring includes regular glucose testing, IGF-1 levels, metabolic panels, insulin sensitivity markers, and clinical assessments

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[126] demonstrated that STAT3 signaling activated the expression of IDO, a major inducer of the immunosuppressive milieu, without the need for binding of STAT3 protein to the promoter of IDO gene in human MDSCs

Read distribution percentages, violin plots, identity heatmaps, and sample MDS plots were generated as part of the QC step using RSeQC [20]