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While clinical research is still lacking, preclinical models suggest that BPC-157 may influence several key systems involved in recovery and cellular repair

Although the use of first-generation uncouplers (e.g., dinitrophenol, DNP) was limited by significant toxicity, subsequent experimental studies and early clinical observations have highlighted the potential benefits of controlled mitochondrial uncoupling in both metabolic diseases and cancer (Goedeke and Shulman, 2021

ICIs have revolutionized melanoma therapy but are often limited by primary or acquired resistance (124, 225)

By focusing on a non-diabetic population, the study minimizes possible confounding effects of hyperglycemia on urinary adverse events