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Am J Physiol Gastrointestinal liver Physiol (2008) 294(4):G87784

Choline enables the liver to metabolize fats effectively, inositol aids in the production of bile necessary for digesting fats, and methionine assists in the detoxification of harmful toxins

the drug was discontinued in 3.6% of the persons in the CagriSema arm compared to 1.3% in the comparators' arms, and observed gastrointestinal adverse events per patient per year were 2.8 with CagriSema versus 2.6 with semaglutide 2.4 mg monotherapy [125]