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As a result, when the stomach is paralyzed, it holds food longer than it should

The mechanism may provide an antioxidant effect by regulating the PI3K/Akt signaling pathway, affecting the downstream GSK3 / - Catenin, and the Nrf2/HO-1 axis (Zhai et al., 2018)

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In any case, we think that the observed effect reflects a mechanism of action inherent to targeting the GLP-1 receptor. Braca said they decided to study the potential impact of GLP-1s on migraine based on previous work done by their research team, which suspected that a derangement in intracranial pressure control plays a role in the pathophysiology of migraine