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In this context, microbiota-targeted interventions such as fecal microbiota transplantation have been proposed as complementary strategies to restore microbial diversity and improve metabolic outcomes, highlighting the broader relevance of hostmicrobiome interactions in shaping antidiabetic drug efficacy (9)

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This reaction takes place in the mitochondrial matrix and is catalyzed by carnitine acyltransferase 2 (also called carnitine palmitoyltransferase 2, CPT2), which is located on the inner face of the inner mitochondrial membrane