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While this risk has not been confirmed in humans, individuals with a personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia Syndrome type 2 should not take Wegovy

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[4] This guide unpacks the gutGLP-1 axis : how a diverse microbiome and the prebiotic fiber that feeds it are connected to your body's natural GLP-1 production, what the peer-reviewed evidence actually shows about fiber, short-chain fatty acids, foods, and specific probiotic species, and how to build an everyday routine that supports the gut environment where this hormone is made