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Sin embargo, los autores advierten que la evidencia sobre los efectos a largo plazo y la seguridad de estos frmacos sigue siendo limitada , en gran parte por la influencia de la financiacin industrial en la mayora de los estudios

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Additional findings are the development of purulent bile enriched in bile pigments and debris, bacterial infection, and intrahepatic stones in the right and left lobes, and extrahepatic ducts

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