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7.2 IGF-1 facilitates cell proliferation and migration The limited number of resident tendon cells is one of the important reasons for the limited inherent regeneration ability of tendons ( Several studies have confirmed that IGF-1 can enhance tenocyte proliferation and migration

Moreover, the senescence phenotype depends on specific pathologies or tissues, making the identification of selective markers essential for the development of new senolytic drug families

Insulin is crucial for those whose bodies do not produce enough of this hormone naturally or cannot utilize it effectively

Those two receptor pathways GIP (glucose-dependent insulinotropic polypeptide) and GLP-1 (glucagon-like peptide-1) are both involved in regulating appetite, blood sugar, and how the body processes food