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Authors contributions Drafting the manuscript, creating figures and tables (WMW), and critically revising the document for important intellectual content (LGL)

Researchers need appropriate insulin syringes for accurate measurement

Abrupt discontinuation can cause appetite rebound, rapid weight regain, blood sugar fluctuations, and other withdrawal effects

Cardiovascular (CV) events are strongly related to interleukin-6 (IL-6) and C-reactive protein (CRP), independently from the classical CV risk factors [1,2,3,4]