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All cognitive neuropeptides in this category are verified by independent double analysis: HPLC chromatography (purity 98%) and LC-MS mass spectrometry (confirmation of the exact molecular mass)

In line with the findings in humans, IGFBP-2 serum concentrations were markedly increased in nephrotic animals despite excessive urinary losses due to increased hepatic synthesis, whereas hepatic synthesis of IGFBP-3 was unchanged compared to controls

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