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The melanocortin system plays a well-documented role in hunger signalling, and studies have examined MT-IIs effects on food intake and energy expenditure

By modulating redox pathways in the cytosol and IMS, we find that the cytosolic glutathione reductase system is the major determinant of E GSH in the IMS, thus explaining a steadystate E GSH in the IMS which is similar to the cytosol

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