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Tribble DL, Gong EL, Leeuwenburgh C, Heinecke JW, Carlson EL, Verstuyft JG, Epstein CJ

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For weight management, semaglutide 2.4 mg once weekly (Wegovy) is initiated at 0.25 mg and gradually escalated over 16 to 20 weeks to minimize gastrointestinal adverse effects

Lejos de indicar una prdida de eficacia, esta meseta puede interpretarse comouna reorganizacin fisiolgica progresiva, en la que los cambios de composicin corporal se vuelven ms lentos pero continan siendo clnicamente relevantes