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No established human neurological treatment can be inferred from these animal studies

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Polymorphic alleles of HRES-1/Rab4 have been associated with autoantibody production and predisposition to autoimmune diseases, such as SLE 31,32 and multiple sclerosis (MS) 33,34

In patients with AITD, autoreactive lymphocytes infiltrate the thyroid parenchyma, where they recognize thyroid antigens: Tg, TPO, TSH-R, and the sodium iodide symporter ( + lymphocytes and cytotoxic CD8 + lymphocytes ( In the pathogenesis of AITD, cells of both adaptive (specific) immunity - CD4 + -, CD8 + -lymphocytes, peripheral regulatory T-cells (pTreg), etc