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Use in Specific Populations Pregnancy: Advise females of potential risk to a fetus especially during the second and third trimesters Lactation: FARXIGA is not recommended when breastfeeding FARXIGA is indicated: as an adjunct to diet and exercise to improve glycemic control in adults and pediatric patients aged 10 years and older with type 2 diabetes mellitus to reduce the risk of hospitalization for heart failure in adults with type 2 diabetes mellitus and either established cardiovascular (CV) disease or multiple CV risk factors to reduce the risk of cardiovascular death, hospitalization for heart failure, and urgent heart failure visit in adults with heart failure to reduce the risk of sustained eGFR decline, end-stage kidney disease, cardiovascular death, and hospitalization for heart failure in adults with chronic kidney disease at risk of progression FARXIGA is not recommended for use to improve glycemic control in patients with type 1 diabetes mellitus

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The hereditary spastic paraplegia-related enzyme DDHD2 is a principal brain triglyceride lipase

The symptom significantly impacts quality of life, as routine activities like wearing clothing, showering, or light contact become sources of distress