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The PNMT gene is located on chromosome 17q12 and is composed of 4 exons that generate two alternatively spliced mRNAs, one of which is non-coding, the other encodes the functional protein of 282 amino acids

Furthermore, individuals with a history of seizure disorders should approach carnitine supplementation with extreme caution, as it has been reported to lower the seizure threshold in susceptible populations

This condition often results from repetitive wrist and forearm movements and can lead to significant discomfort and functional impairment

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