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For example: Around a strained Achilles tendon Near a rotator cuff injury SubQ in the abdomen for systemic inflammation Localized delivery may enhance growth factor expression and collagen synthesis directly at the site of damage

This is in contrast to the report of Kander et al

Antiosteoporotic and selective estrogen receptor modulator In one study silymarin intake could increase the parathormone concentration in ovariectomized -induced bone loss that had leaded to trabecula thickness of the femur and had a positive effect on bone formation