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GLP-1 receptor agonists mimic or enhance the action of glucagon-like peptide-1, an incretin hormone involved in post-meal glucose control, insulin secretion, glucagon suppression, gastric emptying, appetite, and satiety

At 2mg/mL, it requires 120 units, which exceeds a standard syringe and needs a larger syringe or split injection

Effect of Tirzepatide versus insulin degludec on liver fat content and abdominal adipose tissue in people with type 2 diabetes (SURPASS-3 MRI): a substudy of the randomised, open-label, parallel-group, phase 3 SURPASS-3 trial

If you have a history of medullary thyroid cancer or a family history of Multiple Endocrine Neoplasia Cancer Syndrome Type 2 (MEN-2), let your provider know before starting semaglutide