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Vitamin E boosts the skins defenses against free radical damage, while also promoting moisture retention and smoothing dehydrated skin

These investigations also suggest that the role of homocysteine might be overcome by other risk factors (eg, hypertension, diabetes, and dyslipidemia) and/or by various protective mechanisms (such as antioxidant intakes and intrinsic antioxidant systems)

& Pandey, R

This section provides a critical overview of representative high-impact studies published between 2019 and June 2025, summarizing model architectures, performance metrics, key predictive features, translational barriers to clinical adoption, and potential future directions in the field