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Caki-1 cells were cultured in McCoys 5A +FBS [pyruvate-free McCoys 5A containing 16 mM glucose (ThermoFisher, 16600082) supplemented with 10% FBS and 1% penicillin/streptomycin] at 37C in 5% CO 2

Chronic respiratory diseases are one of the leading causes of morbidity and mortality worldwide with many efforts focused on understanding the mechanisms underlying and treatments for these diseases

Enhances Red Blood Cell formation which is crucial for preventing anaemia and maintaining overall health

Therefore, understanding whether IF can mitigate these factors by improving both inflammatory and oxidative stress markers, as well as liver enzyme profiles, could offer a novel, non-pharmacological strategy for managing RA and its associated metabolic complications in this vulnerable population