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In addition, the use of GLP-1 RAs has significantly reduced the risk of mortality, MACE, and MAKE in patients requiring metformin or insulin therapy, suggesting the cost-effectiveness of GLP-1 RAs in these high-risk patients 41

The STEP (Semaglutide Treatment Effects in People with Obesity) trial was conducted to evaluate the role of semaglutide in weight management

Prioritise balanced nutrition , especially enough protein, iron, and essential vitamins Avoid very restrictive dieting , which can increase shedding Be gentle with your hair , limiting heat styling and harsh treatments Consider clinically supported treatments , such as: topical minoxidil caffeine shampoos finasteride (for men, if suitable) If you notice sudden or severe hair loss, or it is affecting your confidence, it is worth speaking to a healthcare professional

Several factors could contribute to this heterogeneity, including differences in study populations, methods of assessing retinopathy, and treatment durations