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These lipid hydroperoxides are unstable and can decompose into secondary oxidative products, such as aldehydes, alkanes, and ketones, with malondialdehyde (MDA) and 4-hydroxynonenal (4-HNE) being notable for their cytotoxic and mutagenic effects [51]

Hepatology 1986

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This hypothesis is also supported by our recent study on flavin-dependent S -oxygenase, which preferably utilizes S -allyl-L-cysteine, rather than -glutamyl- S -allyl-L-cysteine, as the substrate (unpublished results)