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Rebouche, 2004 L-

Adverse immunological effects and autoimmunity induced by dental amalgam and alloy in mice

In conclusion: The administration of cannabis decreases brain oxidative stress but exerts depressive-like effect and decreases rearing activity which can be reversed by antidepressant drugs

The B6 here (26 mg as P5P) sits well under the 100 mg upper limit, but prolonged high-dose B6 has been associated with tingling or numbness in the hands and feet in some people