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There was also a trend towards a significant main effect of treatment (main effect of treatment: F( 1,47 ) = 3.095, p 2 = 0.062, p = 0.085), but no other significant main effects of interactions ( p 0.342)

This offer is beneficial for those who are paying out-of-pocket for their medication

Slower titration is worth considering if: Nausea persists beyond 2 weeks at your current dose You experience significant GI symptoms that interfere with daily function Your body aches or muscle pain are severe You are losing weight faster than 1 to 2 percent of body weight per week (too-rapid weight loss increases muscle loss risk) Some researchers use a 6 or 8-week interval between dose increases instead of the standard 4 weeks

An application for medical approval is already with US authorities, and a decision is expected in the second half of 2026