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The duration of eczema varies

Gu J, Pauer GJT, Yue X, Narendra U, Sturgill GM, Bena J et al (2009) Assessing susceptibility to age-related macular degeneration with proteomic and genomic biomarkers

In the cytoplasm, Keap1 homodimer forms ubiquitin E3 ligase complex with cullin 3 (Cul3), which polyubiquitinates Nrf2 protein leading to its continuous proteasomal degradation ( Figure 3, right)