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Xarelto (Rivaroxaban) Xarelto 2023 Sales: $6.793 billion Company/ Developer: Bayer AG, marketed in collaboration with Janssen Pharmaceuticals (a Johnson & Johnson company) Date of First FDA Approval: July 1, 2011 Indications Xarelto Is FDA-Approved for: Reducing the risk of stroke and systemic embolism in individuals with atrial fibrillation