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Other findings have also suggested that semaglutide might play a role in protecting, or potentially even promoting, cartilage health, bolstering the cushioning tissue within your knee joint

This may include: Review of medication history and dose escalation schedule Dietary assessment and advice from a dietitian Blood tests including amylase, lipase, liver function, and coeliac serology if indicated Consideration of imaging or endoscopy if symptoms suggest structural pathology Patients should never discontinue Ozempic without medical advice (except if pancreatitis is suspected), as abrupt cessation can lead to deterioration in glycaemic control

That felt directly relevant to what I was experiencing

Levels of anti-inflammatory genera such as Faecalibacterium and Eubacterium rectale are often lower in AD, whereas certain pro-inflammatory or opportunistic taxa (like Escherichia/Shigella ) are enriched [125, 126]