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More recently, LEENE, a long non-coding RNA induced downstream of KLF2/KLF4 has been shown to form proximity association with the eNOS promoter and enhances eNOS transcription through chromatin association (Miao et al., 2018)

Histological analysis revealed that Dihexa treatment increased neuronal cell counts and enhanced expression of synaptophysin (SYP), a presynaptic protein marker indicating synaptic density, in the hippocampus of APP/PS1 mice