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Atualmente existem medicamentos aprovados para obesidade e diabetes tipo 2 que atuam em receptores relacionados, como agonistas de GLP-1 e agonistas duais de GLP-1/GIP, que j possuem registro em diversas agncias regulatrias

Although certain probiotic strains have shown potential benefits in modulating the immune system and reducing inflammation, their long-term effects and interactions with other treatments remain unclear

Researchers believe this may be due to how GLP-1 affects the gut by: Slowing motility Modulating nerve signaling Possibly reducing visceral hypersensitivity (pain response) There is also some early evidence that GLP-1 medications may reduce overall IBS symptom severity and medication use, although more long-term data is needed 6

These conditions carry risk of life-threatening complications when combined with GLP-1 therapy