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However, another study showed the process of ferroptosis may exacerbate proteinuria, damaging renal tubules and promoting renal fibrosis via the HIF-1/HO-1 pathway in diabetes models

The impact of GLP-1 analogs on muscle mass is of particular concern, as a reduction in muscle mass can lead to sarcopenia, which negatively affects metabolic health and increases the risk of frailty in the elderly

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