Whereas the first randomized, double-blind, cross-over study with bilateral cathodal cerebellar stimulation showed no effect on essential tremor [155], the second study in which anodal tDCS was applied over the dorsolateral prefrontal cortex showed an improvement in ADL (i.e., Activities of Daily Living) scores and TETRAS (i.e., The Essential Tremor Rating Assessment Scale) scores [211]
This dual mechanism is what makes it the most effective weight loss medication ever studied in clinical trials
"Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) and suicidality: A replication study using reports to the World Health Organization pharmacovigilance database (VigiBase)." Journal of Affective Disorders, 2024
In people with type 2 diabetes or specific cardiovascular risk factors, these can include improvements in insulin sensitivity, reduction in inflammatory markers, favourable effects on lipid profiles (particularly triglycerides), and potential cardiovascular benefits
