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Overexpression of IGF-I in skeletal muscle of transgenic mice does not prevent unloading-induced atrophy

Evidence from Clinical Trials on Weight Loss and Body Composition Liraglutide-based clinical evidence from the SCALE (Satiety and Clinical Adiposity-Liraglutide Evidence) trials (NCT01272219 and NCT01272232), which included older adults within the adult study population, reported that a 56-week intervention with liraglutide 3 mg/day as an adjunct to lifestyle modification resulted in significant weight loss compared with placebo [41, 42]

doi:10.1016/j.path.2009.08.005

Age, sex, BMI, glycated hemoglobin (HbA1c), systolic blood pressure (SBP), and lipid levels were derived from trial data