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Insufficient protein intake, excessive calorie restriction, or irregular injection timing can also stall progress

Human research dosing is typically in the range of 250500 mcg daily, administered subcutaneously or orally (noting that oral bioavailability data in humans is limited)

[DOI] [PubMed] [Google Scholar] 59.El-Shitany NA, Hegazy S, El-desoky K

Following this, Banting signed a contract with Connaught Laboratories of the University of Toronto for the large-scale production of their insulin extract which they used to successfully treat a further six patients