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eds.), pp20741

22 describes iPSCs to better resemble fetal cardiomyocytes (regarding structure, proliferation, metabolism and electrophysiology) rather than adult cardiomyocytes

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Therefore, future clinical translation will probably benefit from biomarker-guided frameworks, incorporating (1) FSP1 abundance/localization, (2) CoQ pool size and redox state, (3) lipid peroxidation signatures and (4) metabolic context (mitochondrial activity and sulfur/selenium flux)