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But the amount of weight people lose varies significantly

Liver Int 34(3):367378 Trauner M, Claudel T, Fickert P, Moustafa T, Wagner M (2010) Bile acids as regulators of hepatic lipid and glucose metabolism

I think what were also seeing is it cuts down on noise across the board for other substances, perhaps the alcohol, opiates, stimulants, maybe even nicotine. Studies on the connection between GLP-1 medications and reduced substance cravings are ongoing