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In microdosing, your healthcare provider may recommend administering the medication every 10 or 14 days

The proposed mechanisms range from well-validated (FDA-approved GLP-1 agonists for weight loss) to highly speculative (epitalon, thymosin alpha-1, MOTS-c) with limited or no human clinical validation

In one randomized study, a resistant maltodextrin (Fibersol) significantly raised GLP-1 and PYY at a 10 g per meal dose but not at 5 g, which illustrates how dose-dependent this endogenous effect is [4]